250694-07-6

250694-07-6 structure

Name: Teglicar
Chemical Name: Teglicar
CAS Number: 250694-07-6
Molecular Formula: C₂₂H₄₅N₃O₃
Molecular Weight: 399.61100
Catalog: Research Areas Metabolic Disease
Create Date: 2018-09-23 12:38:59
Modify Date: 2024-01-09 17:36:21
Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1].

Name	Teglicar
Synonyms	(R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate ST 1326 3-(TETRADECYLCARBAMOYLAMINO)-4-TRIMETHYLAMMONIO-BUTANOATE 1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-,inner salt,(2R) R-4-trimethylammonium-3-(tetradecylcarbamoyl)-aminobutyrate 3-(tetradecylcarbamoylamino)-4-(trimethylazaniumyl)butanoate 4-trimethylammonium-(R)-3-(tetradecylcarbamoyl)-amino butyrate

Description	Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	IC50: L-CPT1[1]
References	[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.