Teglicar

Modify Date: 2024-01-09 17:36:21

Teglicar Structure
Teglicar structure
Common Name Teglicar
CAS Number 250694-07-6 Molecular Weight 399.61100
Density N/A Boiling Point N/A
Molecular Formula C22H45N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Teglicar


Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1].

 Names

Name Teglicar
Synonym More Synonyms

 Teglicar Biological Activity

Description Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). Teglicar reduces ketogenesis and glucose production, decreases gluconeogenesis and improves glucose homeostasis. Teglicar has a potential antihyperglycemic propert[1].
Related Catalog
Target

IC50: L-CPT1[1]

References

[1]. Conti R, et al. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb;60(2):644-51.

 Chemical & Physical Properties

Molecular Formula C22H45N3O3
Molecular Weight 399.61100
Exact Mass 399.34600
PSA 81.26000
LogP 3.98330

 Synonyms

(R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate
ST 1326
3-(TETRADECYLCARBAMOYLAMINO)-4-TRIMETHYLAMMONIO-BUTANOATE
1-Propanaminium,3-carboxy-N,N,N-trimethyl-2-[[(tetradecylamino)carbonyl]amino]-,inner salt,(2R)
R-4-trimethylammonium-3-(tetradecylcarbamoyl)-aminobutyrate
3-(tetradecylcarbamoylamino)-4-(trimethylazaniumyl)butanoate
4-trimethylammonium-(R)-3-(tetradecylcarbamoyl)-amino butyrate
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