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548-08-3

548-08-3 structure
548-08-3 structure
  • Name: Roemerine
  • Chemical Name: (–)-roemerine
  • CAS Number: 548-08-3
  • Molecular Formula: C18H17NO2
  • Molecular Weight: 279.33300
  • Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridazine
  • Create Date: 2018-02-27 08:00:00
  • Modify Date: 2024-01-02 17:59:00
  • Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].

Name (–)-roemerine
Synonyms (6aR)-roemerine
(R)-(-)-roemerine
(-)-romerine
Roemerine
(-)-Aporheine
(-)-Remerine
(-)-Roemarine
Description Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1].
Related Catalog
References

[1]. M You, et al. (-)-Roemerine, an Aporphine Alkaloid From Annona Senegalensis That Reverses the Multidrug-Resistance Phenotype With Cultured Cells. J Nat Prod. 1995 Apr;58(4):598-604.

Density 1.269±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point 102-103 ºC
Molecular Formula C18H17NO2
Molecular Weight 279.33300
Exact Mass 279.12600
PSA 21.70000
LogP 3.10530
Hazard Codes Xi
Precursor  0

DownStream  1