Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Tipiracil hydrochloride
Price: ￥2536.0/250mg ￥1946.0/100mg ￥736.0/10mg ￥506.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Tipiracil hydrochloride
Price: $400.0/100mg $700.0/250mg $1350.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-Chloro-6-(2-iminopyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Tipiracil
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

183204-72-0

183204-72-0 structure

183204-72-0 structure

Name: Tipiracil hydrochloride
Chemical Name: 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione,hydrochloride
CAS Number: 183204-72-0
Molecular Formula: C₉H₁₂Cl₂N₄O₂
Molecular Weight: 279.123
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-10 16:55:16
Modify Date: 2024-01-02 18:42:52
Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

Name	5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione,hydrochloride
Synonyms	Tipiracil HCl 5-amino-1-[(5-chloro-2,6-dihydroxypyrimidin-4-yl)methyl]-3,4-dihydro-2H-pyrrolium chloride 2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1) TAS-1-462 Tipiracil hydrochloride 2H-pyrrolium, 5-amino-1-[(5-chloro-2,6-dihydroxy-4-pyrimidinyl)methyl]-3,4-dihydro-, chloride (1:1) 5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride (1:1) Tipiracil hydrochloride (JAN)

Description	Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Cancer
In Vitro	Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells[1]. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD[2].
References	[1]. Peters GJ, et al. TAS-102: more than an antimetabolite. Lancet Oncol. 2012 Dec;13(12):e518-9. [2]. Yoshino T, et al. TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol. 2012 Oct;13(10):993-1001.

Molecular Formula	C₉H₁₂Cl₂N₄O₂
Molecular Weight	279.123
Exact Mass	278.033722
PSA	93.33000
LogP	1.95390
Storage condition	2-8°C

RIDADR	NONH for all modes of transport