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5424-20-4

5424-20-4 structure
5424-20-4 structure

Name tannic acid
Synonyms Quebracho extract
DSSTox_CID_6076
gallotannin
Gallotannic acid
penta-m-digalloyl-glucose
gallotanine
Tanninum
decagalloyl glucose
Description Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].
Related Catalog
Target

Ki: 0.82 μg/mL (Human Salivary α-Amylase)[1] IC50: 2.3 μg/mL (Porcine Pancreatic α-Amylase), 128.9 nM (Telomerase), 3.0 μM (Fatty acid synthase), 6.9 μM (α-Ketoglutarate-Dependent Dioxygenase AlkB), 7.8 μM (5α-Reductase), 24.2 μM (Poly(ADP-ribose) Glycohydrolase)[1]

References

[1]. Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97(2):349-357.  

Density 2.12 g/cm3
Boiling Point 198ºC
Melting Point 218ºC(lit.)
Molecular Formula C76H52O46
Molecular Weight 1701.20
Flash Point 198 °C
Exact Mass 1700.17000
PSA 777.98000
LogP 4.83810
Index of Refraction 1.927
Safety Phrases 24/25
WGK Germany 2
RTECS WW5075000
HS Code 3201909000
Precursor  0

DownStream  2

HS Code 3201909000