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605-65-2

605-65-2 structure
605-65-2 structure
  • Name: Dansyl chloride
  • Chemical Name: dansyl chloride
  • CAS Number: 605-65-2
  • Molecular Formula: C12H12ClNO2S
  • Molecular Weight: 269.747
  • Catalog: Chemical reagent Organic reagent Sulfonate/sulfinate
  • Create Date: 2018-02-13 08:00:00
  • Modify Date: 2024-01-02 20:33:03
  • Dansyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis. It can also be used to label hydroxyl and carboxylic acid functional groups.
Name dansyl chloride
Synonyms 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
EINECS 210-092-6
5-(Dimethylamino)-1-naphthalenesulfonyl chloride
MFCD00003985
1-chlorosulfonyl-5-(dimethylamino)naphthalene
Dansyl chloride
1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-
Description Dansyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis. It can also be used to label hydroxyl and carboxylic acid functional groups.
Related Catalog
Density 1.4±0.1 g/cm3
Boiling Point 371.3±22.0 °C at 760 mmHg
Melting Point 72-74 °C(lit.)
Molecular Formula C12H12ClNO2S
Molecular Weight 269.747
Flash Point 178.4±22.3 °C
Exact Mass 269.027740
PSA 45.76000
LogP 3.67
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.636
Storage condition 2-8°C
Water Solubility acetone: 50 mg/mL

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK3688000
CHEMICAL NAME :
1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-
CAS REGISTRY NUMBER :
605-65-2
BEILSTEIN REFERENCE NO. :
2217205
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H12-Cl-N-O2-S
MOLECULAR WEIGHT :
269.76
WISWESSER LINE NOTATION :
L66J BSWG GN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00262
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS QK3688000
Packaging Group III
Hazard Class 8
HS Code 29214980
HS Code 2921199090
Summary 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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