Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Rifamycin SV, 8-(diethylaminomethyl)-
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Purity: 98.0%
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4075-41-6

4075-41-6 structure

4075-41-6 structure

Name: Rifamycin SV, 8-(diethylaminomethyl)-
Chemical Name: Rifamycin PF 42
CAS Number: 4075-41-6
Molecular Formula: C₄₂H₅₈N₂O₁₂
Molecular Weight: 782.91600
Create Date: 2017-02-02 18:41:22
Modify Date: 2024-04-03 11:51:58

Name	Rifamycin PF 42
Synonyms	PF-42 Rifamycin,3-[(diethylamino)methyl] Rifamycin SV,8-(diethylaminomethyl) 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(diethylaminomethyl)-,21-acetate 3-(diethylamino-methyl)-rifamycin 3-Diethylaminomethyl rifamycin SV NCI 145-666 3-Diaethylaminomethyl-rifamycin SV

Density	1.3g/cm3
Boiling Point	877.6ºC at 760 mmHg
Molecular Formula	C₄₂H₅₈N₂O₁₂
Molecular Weight	782.91600
Flash Point	484.5ºC
Exact Mass	782.39900
PSA	204.55000
LogP	5.73390
Index of Refraction	1.618

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KD1920250

CHEMICAL NAME :: 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(diethylaminomethy l)-, 21-acetate

CAS REGISTRY NUMBER :: 4075-41-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C42-H58-N2-O12

MOLECULAR WEIGHT :: 783.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 205 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977