4075-41-6

• 常用中文名：Rifamycin SV, 8-(diethylaminomethyl)-
• 常用英文名：Rifamycin SV, 8-(diethylaminomethyl)-
• CAS号：4075-41-6
• 分子式：C₄₂H₅₈N₂O₁₂
• 分子量：782.91600
• 发布时间：2017-02-02 18:41:22
• 更新时间：2025-09-05 15:55:18

名称

• 英文名: Rifamycin PF 42
• 英文别名: PF-42; Rifamycin,3-[(diethylamino)methyl]; Rifamycin SV,8-(diethylaminomethyl); 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(diethylaminomethyl)-,21-acetate; 3-(diethylamino-methyl)-rifamycin; 3-Diethylaminomethyl rifamycin SV; NCI 145-666; 3-Diaethylaminomethyl-rifamycin SV

物化性质

• 密度: 1.3g/cm3
• 沸点: 877.6ºC at 760 mmHg
• 分子式: C₄₂H₅₈N₂O₁₂
• 分子量: 782.91600
• 闪点: 484.5ºC
• 精确质量: 782.39900
• PSA: 204.55000
• LogP: 5.73390
• 折射率: 1.618

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KD1920250 CHEMICAL NAME : 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(diethylaminomethy l)-, 21-acetate CAS REGISTRY NUMBER : 4075-41-6 LAST UPDATED : 199712 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C42-H58-N2-O12 MOLECULAR WEIGHT : 783.02 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 205 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977