518357-51-2

518357-51-2 structure

Name: 3-MATIDA
Chemical Name: 5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid
CAS Number: 518357-51-2
Molecular Formula: C₈H₉NO₄S
Molecular Weight: 215.23
Catalog: Research Areas Neurological Disease
Create Date: 2016-05-09 03:11:16
Modify Date: 2025-08-25 19:39:14
3-MATIDA is a metabolic glutamate 1 (mGlu1) receptor antagonist. 3-MATIDA alleviates neuronal death in cerebral ischemia models. 3-MATIDA can be used in the study of neuronal injury and epileptiform activity after ischemia [1].

Name	5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid
Synonyms	3-matida hms3268b08

Description	3-MATIDA is a metabolic glutamate 1 (mGlu1) receptor antagonist. 3-MATIDA alleviates neuronal death in cerebral ischemia models. 3-MATIDA can be used in the study of neuronal injury and epileptiform activity after ischemia [1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Cozzi A, et al. Metabotropic glutamate 1 (mGlu1)receptor antagonists enhance GABAergic neurotransmission: a mechanism for theattenuation of post-ischemic injury and epileptiform activity?Neuropharmacology. 2002 Aug;43(2):119-30.