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577969-56-3

577969-56-3 structure
577969-56-3 structure
  • Name: Ac-Gly-Ala-Lys(Ac)-AMC
  • Chemical Name: acetyl-Gly-Ala-(N-acetyl-Lys)-AMC
  • CAS Number: 577969-56-3
  • Molecular Formula: C25H33N5O7
  • Molecular Weight: 515.56
  • Catalog: Research Areas Others
  • Create Date: 2017-11-17 14:33:10
  • Modify Date: 2025-09-07 16:32:06
  • Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

Name acetyl-Gly-Ala-(N-acetyl-Lys)-AMC
Synonyms AC-GLY-ALA-LYS(AC)-AMC
Ac-GAK(Ac)-AMC
Description Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related Catalog
References

[1]. Ptacek J, et, al. Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells. Int J Mol Sci. 2023 Mar 1;24(5):4720.  

Molecular Formula C25H33N5O7
Molecular Weight 515.56
Exact Mass 515.23800
PSA 175.71000
LogP 2.10850
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