87064-61-7

87064-61-7 structure

Name: Euphohelioscopin A
Chemical Name: euphohelioscopin A
CAS Number: 87064-61-7
Molecular Formula: C₃₀H₄₂O₆
Molecular Weight: 498.65
Catalog: Natural product Moss
Create Date: 2016-06-13 05:04:41
Modify Date: 2024-01-09 20:35:14
Euphohelioscopin A is a diterpenoid can be isolated from the Euphorbia helioscopia L. plant. Euphohelioscopin A weakly inhibits P-glycoprotein-mediated efflux of mitoxantrone[1].

Name	euphohelioscopin A
Synonyms	(1aR,2Z,4aR,6R,7S,7aS,8Z,10R,11aS)-4a-Acetoxy-7-hydroxy-1,1,3,6,9-pentamethyl-4-oxo-1a,4,4a,5,6,7,7a,10,11,11a-decahydro-1H-cyclopenta[a]cyclopropa[f][11]annulen-10-yl (2E,4Z)-2,4-octadienoate 2,4-Octadienoic acid, (1aR,2Z,4aR,6R,7S,7aS,8Z,10R,11aS)-4a-(acetyloxy)-1a,4,4a,5,6,7,7a,10,11,11a-decahydro-7-hydroxy-1,1,3,6,9-pentamethyl-4-oxo-1H-cyclopenta[a]cyclopropa[f]cycloundecen-10-yl ester, (2E,4Z)-

Description	Euphohelioscopin A is a diterpenoid can be isolated from the Euphorbia helioscopia L. plant. Euphohelioscopin A weakly inhibits P-glycoprotein-mediated efflux of mitoxantrone[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. Barile E, et al. Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators. Org Biomol Chem. 2008 May 21;6(10):1756-62.