Top Suppliers:I want be here



15307-93-4

15307-93-4 structure
15307-93-4 structure

Name 2,6-Dichlorodiphenylamine
Synonyms 2,6-DICHLORODIPHENYLAMINE
N-Phenyl-2,6-dichloroaniline
2,6-Dichloro-N-phenylaniline
EINECS 239-349-0
MFCD00269648
N-(2,6-Dichlorophenyl)aniline
Benzenamine, 2,6-dichloro-N-phenyl-
Diclofenac Impurity 6
Description 2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.
Related Catalog
References

[1]. Makoto Urai,et al. Potent Drugs That Attenuate anti-Candida Albicans Activity of Fluconazole and Their Possible Mechanisms of Action. J Infect Chemother. 2014 Oct;20(10):612-5.

Density 1.3±0.1 g/cm3
Boiling Point 309.8±32.0 °C at 760 mmHg
Melting Point 50-53 °C(lit.)
Molecular Formula C12H9Cl2N
Molecular Weight 238.113
Flash Point 141.2±25.1 °C
Exact Mass 237.011200
PSA 12.03000
LogP 4.77
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.650
2,6-Dichlorodiphenylamine Revision number: 5
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:2,6-Dichlorodiphenylamine

Revision number:5

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS
Skin corrosion/irritationCategory 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDSNot classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal wordWarning
Hazard statementsCauses skin irritation
Causes serious eye irritation
Precautionary statements:
Wash hands thoroughly after handling.
[Prevention]
Wear protective gloves/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
[Response]
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:2,6-Dichlorodiphenylamine
Percent:>98.0%(GC)
CAS Number:15307-93-4
Synonyms:N-(2,6-Dichlorophenyl)aniline
C12H9Cl2N
Chemical Formula:

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
2,6-Dichlorodiphenylamine

Section4. FIRST AID MEASURES
Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth.
A rescuer should wear personal protective equipment, such as rubber gloves and air-
Protection of first-aiders:
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Suitable extinguishingDry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical:generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls:Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Safety glasses. A face-shield, if the situation requires.
Eye protection:
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Crystal- Powder
Form:
Colour:White - Greyish yellow green
No data available
Odour:
2,6-Dichlorodiphenylamine

Section9. PHYSICAL AND CHEMICAL PROPERTIES
pH: No data available
Melting point/freezing point:51°C
Boiling point/range:No data available
Flash point:No data available
Flammability or explosive
limits:
Lower:No data available
Upper:No data available
Relative density:No data available
Solubility(ies):
[Water]No data available
[Other solvents]
Soluble:Methanol

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
products:

Section11. TOXICOLOGICAL INFORMATION
Acute Toxicity:No data available
Skin corrosion/irritation: No data available
Serious eyeNo data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
Reproductive toxicity:No data available

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
No data available
Algae:
Persistence / degradability: No data available
No data available
Bioaccumulative
potential(BCF):
Mobility in soil
Log Pow:No data available
Soil adsorption (Koc):No data available
Henry's LawNo data available
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
UN-No:Not listed
2,6-Dichlorodiphenylamine

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H315-H319-H410
Precautionary Statements P273-P305 + P351 + P338-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR UN 3077 9 / PGIII
WGK Germany 3
HS Code 2921440000

~83%

15307-93-4 structure

15307-93-4

Literature: Osaka Yuki Kagaku Kogyo Kabushiki Kaisha Patent: US4908479 A1, 1990 ;

~89%

15307-93-4 structure

15307-93-4

Literature: Yung Shin Pharm. Ind. Co., Ltd. Patent: US5475139 A1, 1995 ;

~94%

15307-93-4 structure

15307-93-4

Literature: Buchwald, Stephen L.; Mauger, Christelle; Mignani, Gerard; Scholz, Ulrich Advanced Synthesis and Catalysis, 2006 , vol. 348, # 1-2 p. 23 - 39

~%

15307-93-4 structure

15307-93-4

Literature: Pharmaceutical Chemistry Journal, , vol. 30, # 1 p. 38 - 40

~%

15307-93-4 structure

15307-93-4

Literature: Pharmaceutical Chemistry Journal, , vol. 30, # 1 p. 38 - 40

~%

15307-93-4 structure

15307-93-4

Literature: Advanced Synthesis and Catalysis, , vol. 348, # 1-2 p. 23 - 39
HS Code 2921440000
Summary 2921440000. diphenylamine and its derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%