29606-06-2

29606-06-2 structure

Name: Ro 20-0657/000
Chemical Name: (2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanol
CAS Number: 29606-06-2
Molecular Formula: C₁₄H₁₈N₄O₄
Molecular Weight: 306.31700
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-06-28 19:30:54
Modify Date: 2024-01-22 15:39:56
Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine[1][2][3].

Name	(2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanol
Synonyms	ro-20-0657/000 unii-7439xp501f

Description	Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Robert E. London, et al. Nuclear magnetic resonance study of interaction of ligands with Streptococcus faecium dihydrofolate reductase labeled with [.gamma.-13C]tryptophan. Biochemistry 1982, 21, 18, 4450-4458. [2]. van 't Klooster GA, et al. Determination of trimethoprim and its oxidative metabolites in cell culture media and microsomal incubation mixtures by high-performance liquid chromatography. J Chromatogr. 1992 Sep 2;579(2):354-60. [3]. Tadić Đ, et al. Simultaneous determination of multiclass antibiotics and their metabolites in four types of field-grown vegetables. Anal Bioanal Chem. 2019 Aug;411(20):5209-5222.

Hazard Codes	Xi