2219-51-4

2219-51-4 structure

Name: 1,2-(2H4)Ethanediol
Chemical Name: ethylene-d4 glycol
CAS Number: 2219-51-4
Molecular Formula: C₂H₂D₄O₂
Molecular Weight: 66.092
Catalog: Organic raw materials Alcohols, phenols, phenolic compounds and derivatives Acyclic alcohol
Create Date: 2018-05-23 08:00:00
Modify Date: 2024-01-03 00:21:48
Ethylene glycol-d4 is the deuterium labeled Ethylene glycol[1].

Name	ethylene-d4 glycol
Synonyms	1,2-(H)Ethanediol d2-hydrogen sulphide deuterium-labeled ethylene glycol (H)Ethane-1,2-diol ethylene glycol-d6 EINECS 218-730-5 MFCD00075388 Hydrogen sulfide-d2 1,2-Ethane-d-diol Ethylene-d4Glycol

Description	Ethylene glycol-d4 is the deuterium labeled Ethylene glycol[1].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Density	1.1±0.1 g/cm3
Boiling Point	197.5±0.0 °C at 760 mmHg
Melting Point	-13ºC(lit.)
Molecular Formula	C₂H₂D₄O₂
Molecular Weight	66.092
Flash Point	108.2±13.0 °C
Exact Mass	66.061890
PSA	40.46000
LogP	-1.69
Vapour Pressure	0.1±0.8 mmHg at 25°C
Index of Refraction	1.422
Storage condition	2-8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S2
RIDADR	UN 3082 9 / PGIII
WGK Germany	3
HS Code	2905310000

95-92-1

~71%

2219-51-4

Literature: AUSPEX PHARMACEUTICALS, INC.; RAO, Tadimeti; ZHANG, Chengzhi Patent: WO2011/17108 A2, 2011 ; Location in patent: Page/Page column 46-47 ; WO 2011/017108 A2

107-21-1

~89%

2219-51-4

Literature: Maegawa, Tomohiro; Fujiwara, Yuta; Inagaki, Yuya; Monguchi, Yasunari; Sajiki, Hironao Advanced Synthesis and Catalysis, 2008 , vol. 350, # 14-15 p. 2215 - 2218

96-49-1

~49%

1849-29-2

2219-51-4

Literature: Angewandte Chemie - International Edition, , vol. 51, # 52 p. 13041 - 13045 Angew. Chem., , vol. 124, # 52

87867-14-9

2219-51-4

Literature: Organic Mass Spectrometry, , vol. 28, # 5 p. 552 - 558

123-25-1

2219-51-4

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 7 p. 720 - 722

Precursor 5
95-92-1 107-21-1 96-49-1 87867-14-9
123-25-1
DownStream 4
22581-63-1 1664-98-8 17060-07-0 764650-43-3

HS Code	2905310000
Summary	HS:2905310000 ethane-1,2-diol VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2219-51-4	100189-81-9
34281-22-6	291765-93-0
1219798-78-3	37164-19-5
202656-22-2	15054-86-1
159474-87-0	288569-83-5