Name | lycorine |
---|---|
Synonyms |
3,3a-Didehydrolycoran-1a,2b-diol
Amarylline (1a,2b)-3,12-Didehydro-9,10-[methylenebis(oxy)]galanthan-1,2-diol (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1S,2S,12bS,12cS)- Lycorine (1S,2S,12bS,12cS)-1,2-diol-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine Galanthidine Belamarine Licorine Narcissine |
Description | Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family with antiviral, antimalarial and antiinflammation activities. Lycorine inhibits the growth and metastasis of hormone-refractory anti-prostate cancer (PCa) and induces cell apoptosis[1]. |
---|---|
Related Catalog | |
In Vitro | Lycorine inhibits cell proliferation in a dose-dependent manner in the abovementioned 4 PCa cell lines, and the IC50 ranged from 5 μM to 10 μM., it also shows Lycorine has little effects on PNT1A cell's proliferation[1]. |
References |
Density | 1.5±0.1 g/cm3 |
---|---|
Boiling Point | 477.4±45.0 °C at 760 mmHg |
Melting Point | 253-255ºC (dec.) |
Molecular Formula | C16H17NO4 |
Molecular Weight | 287.310 |
Flash Point | 242.5±28.7 °C |
Exact Mass | 287.115753 |
PSA | 62.16000 |
LogP | 0.77 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.733 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Hazard Codes | T: Toxic; |
---|---|
Risk Phrases | R25 |
Safety Phrases | 45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
Hazard Class | 9.0 |
Precursor 8 | |
---|---|
DownStream 3 | |