Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DSLET
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: [D-Ser2] Leu-Enkephalin-Thr
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

75644-90-5

75644-90-5 structure

75644-90-5 structure

Name: (D-Ser2)-Leu-Enkephalin-Thr
Chemical Name: dslet
CAS Number: 75644-90-5
Molecular Formula: C₃₃H₄₆N₆O₁₀
Molecular Weight: 686.753
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2018-12-26 12:48:00
Modify Date: 2025-08-25 09:02:07
DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor[1][2].

Name	dslet
Synonyms	M.W. 686.90 C33H46N6O10 L-Threonine, L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl- D-Ser2,Leu5,Thr6-enkephalin L-Tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine Dislet Dstle TYR-D-SER-GLY-PHE-LEU-THR 2-Ser-Thr-Leu-enkephalin [D-Ser2] Leu-Enkephalin-Thr

Description	DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	δ Opioid Receptor/DOR
In Vitro	DSLET (0.1-1000 μM) 以剂量依赖性方式抑制霍乱毒素 (CT; HY-P1446) 诱导的 cAMP 生成[1]。
References	[1]. J L Nano, et al. Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line. Pflugers Arch. 2000 Mar;439(5):547-54. [2]. C S Goodchild, et al. Antinociception by intrathecal midazolam involves endogenous neurotransmitters acting at spinal cord delta opioid receptors. Br J Anaesth. 1996 Dec;77(6):758-63.

Density	1.3±0.1 g/cm3
Boiling Point	1163.0±65.0 °C at 760 mmHg
Molecular Formula	C₃₃H₄₆N₆O₁₀
Molecular Weight	686.753
Flash Point	657.2±34.3 °C
Exact Mass	686.327515
PSA	269.51000
LogP	1.09
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.592
Storage condition	-20°C

78537-18-5 structure

78537-18-5

~90%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

3978-80-1 structure

3978-80-1

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

78537-15-2 structure

78537-15-2

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

78537-13-0 structure

78537-13-0

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

78565-55-6 structure

78565-55-6

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

78537-16-3 structure

78537-16-3

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

78537-17-4 structure

78537-17-4

~%

75644-90-5 structure

75644-90-5

Literature: Gacel, Gilles; Fournie-Zaluski, Marie-Claude; Fellion, Etienne; Roques, Bernard P. Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1119 - 1124

Precursor 7
78537-18-5 3978-80-1 78537-15-2 78537-13-0
78565-55-6 78537-16-3 78537-17-4
DownStream 0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.