173952-44-8
173952-44-8 structure
- Name: SYM2206
- Chemical Name: SYM 2206,(±)-4-(4-Aminophenyl)-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine
- CAS Number: 173952-44-8
- Molecular Formula: C20H22N4O3
- Molecular Weight: 366.41400
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2016-03-25 16:24:40
- Modify Date: 2025-09-21 11:15:03
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SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM).IC50 value: 2.8 μMTarget: AMPA receptorSYM 2206 exerts anticonvulsant effects, elevates the threshold for maximal electroshock-induced seizures in mice. TID20 and TID50(threshold increasing doses by 20% and 50%) values for SYM 2206 are 4.25 and 10.56 mg/kg in the MEST test in mice, respectively.
| Name | SYM 2206,(±)-4-(4-Aminophenyl)-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine |
|---|---|
| Synonyms |
TRIS hydrochloride
SYM 2206 SYM2206 |
| Description | SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8 μM).IC50 value: 2.8 μMTarget: AMPA receptorSYM 2206 exerts anticonvulsant effects, elevates the threshold for maximal electroshock-induced seizures in mice. TID20 and TID50(threshold increasing doses by 20% and 50%) values for SYM 2206 are 4.25 and 10.56 mg/kg in the MEST test in mice, respectively. |
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| Related Catalog | |
| References |
| Density | 1.37g/cm3 |
|---|---|
| Molecular Formula | C20H22N4O3 |
| Molecular Weight | 366.41400 |
| Exact Mass | 366.16900 |
| PSA | 89.18000 |
| LogP | 3.59170 |
| Index of Refraction | 1.673 |
| Storage condition | 2-8℃ |