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  • Product Name: Ethyl ferulate
  • Price: ¥Inquiry/50mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng




4046-02-0

4046-02-0 structure
4046-02-0 structure
  • Name: Ethyl ferulate
  • Chemical Name: Ethyl 4'-hydroxy-3'-methoxycinnamate
  • CAS Number: 4046-02-0
  • Molecular Formula: C12H14O4
  • Molecular Weight: 222.24
  • Catalog: Chemical reagent Organic reagent Ester Ethyl ester compound
  • Create Date: 2018-04-07 08:00:00
  • Modify Date: 2024-01-02 22:13:07
  • Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2].

Name Ethyl 4'-hydroxy-3'-methoxycinnamate
Synonyms ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
MFCD00009190
4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester
Ferulic acid ethyl ester
Ethyl 4-Hydroxy-3-MethoxycinnaMate
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester
EINECS 223-745-5
Ethyl Ferulate
Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
Description Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2].
Related Catalog
References

[1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8.

[2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58.

Density 1.2±0.1 g/cm3
Boiling Point 382.3±0.0 °C at 760 mmHg
Melting Point 63-65 °C(lit.)
Molecular Formula C12H14O4
Molecular Weight 222.24
Flash Point 132.5±17.2 °C
Exact Mass 222.089203
PSA 55.76000
LogP 1.94
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.566
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918990090

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Literature: Molecules, , vol. 14, # 6 p. 2118 - 2126

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Literature: Organic Letters, , vol. 14, # 15 p. 3902 - 3905

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Literature: Journal of the American Chemical Society, , vol. 134, # 46 p. 18889 - 18891

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Literature: Tetrahedron, , vol. 57, # 2 p. 365 - 370

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Literature: Liebigs Annalen der Chemie, , # 12 p. 2135 - 2140

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Literature: Chemische Berichte, , vol. 85, p. 1181,1188
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%