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504-03-0

504-03-0 structure
504-03-0 structure
  • Name: nanofin
  • Chemical Name: 2,6-Dimethylpiperidine
  • CAS Number: 504-03-0
  • Molecular Formula: C7H15N
  • Molecular Weight: 113.201
  • Catalog: API Circulatory system medication Antihypertensive drug
  • Create Date: 2018-04-17 08:00:00
  • Modify Date: 2024-01-04 19:00:41
  • Nanofin is neuropathic blocker, with antihypertensive effect, used for mild to moderate hypertension.

Name 2,6-Dimethylpiperidine
Synonyms nanofin
2,6-lupetidine
Nanophine
Nanophin
UNII:329I5805BP
nanofine
2,6-di-methylpiperidine
naniopine
bolandiol
Lupetidin
2,6-dimethylpiperidin
2,6-Dimethylpiperidine
MFCD00005986
Naniopin
Piperidine, 2,6-dimethyl-
EINECS 207-981-6
2,5-DIMETHYL-1-(TETRAHYDROFURAN-2-YLMETHYL)-1H-PYRROLE-3-CARBALDEHYDE
Description Nanofin is neuropathic blocker, with antihypertensive effect, used for mild to moderate hypertension.
Related Catalog
Density 0.8±0.1 g/cm3
Boiling Point 127.1±0.0 °C at 760 mmHg
Melting Point <-20ºC
Molecular Formula C7H15N
Molecular Weight 113.201
Flash Point 11.7±0.0 °C
Exact Mass 113.120445
PSA 12.03000
LogP 1.92
Vapour Pressure 11.3±0.2 mmHg at 25°C
Index of Refraction 1.417
Storage condition Flammables area
Water Solubility MISCIBLE
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 2,6-Dimethylpiperidine
Synonyms:2,6-Lupetidine

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:2,6-Dimethylpiperidine
CAS number:504-03-0

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C7H15N
Molecular weight:113.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OK5775000
CHEMICAL NAME :
2,6-Lupetidine
CAS REGISTRY NUMBER :
504-03-0
BEILSTEIN REFERENCE NO. :
0079827
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H15-N
MOLECULAR WEIGHT :
113.23
WISWESSER LINE NOTATION :
T6MTJ B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BDCGAS Berichte der Deutschen Chemischen Gesellschaft. (Leipzig, Ger. Dem. Rep.) V.1-61, 1868-1928. For publisher information, see CHBEAM. Volume(issue)/page/year: 34,2408,1901
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
625 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,595,1948
Hazard Codes F: Flammable;C: Corrosive;
Risk Phrases R11;R34
Safety Phrases S16-S26-S36/37/39
RIDADR UN 1993 3/PG 2
WGK Germany 3
RTECS OK5775000
Packaging Group II
Hazard Class 3
HS Code 2933399090

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504-03-0 structure

504-03-0

Literature: Kim, Young Kwan; Livinghouse, Tom Angewandte Chemie - International Edition, 2002 , vol. 41, # 19 p. 3645 - 3647

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504-03-0

Literature: Boga; Manescalchi; Savoia Tetrahedron, 1994 , vol. 50, # 16 p. 4709 - 4722

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504-03-0

Literature: Singer, Sandra S.; Singer, George M.; Cole, Barbara B. Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4931 - 4935

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504-03-0 structure

504-03-0

Literature: Ogura, Tomohito; Higashihara, Tomoya; Ueda, Mitsuru Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 6 p. 1317 - 1323

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504-03-0

Literature: Dannan; Crooks; Dittert; Hussain Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 7 p. 652 - 656
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%