937188-60-8
937188-60-8 structure
- Name: HO-PEG8-CH2CH2COOH
- Chemical Name: Propanoic acid, 3-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]
- CAS Number: 937188-60-8
- Molecular Formula: C19H38O11
- Molecular Weight: 442.49800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-05-29 04:50:46
- Modify Date: 2024-01-09 18:50:21
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HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Propanoic acid, 3-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy] |
|---|---|
| Synonyms |
HO-PEG8-CH2CH2COOH
Alpha-hydroxy-ω-propionic acid octaethylene glycol |
| Description | HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.148±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 554.3±50.0 °C (760 mmHg) |
| Molecular Formula | C19H38O11 |
| Molecular Weight | 442.49800 |
| Exact Mass | 442.24100 |
| PSA | 131.37000 |
| Hazard Codes | Xi |
|---|