89665-83-8

89665-83-8 structure

Name: 5-(Carboxy(hydroxy)methyl)uridine methyl ester
Chemical Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetate
CAS Number: 89665-83-8
Molecular Formula: C₁₂H₁₆N₂O₉
Molecular Weight: 332.26300
Catalog: Research Areas Others
Create Date: 2016-09-08 04:58:56
Modify Date: 2024-09-18 15:10:11
(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis[1].

Name	methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetate
Synonyms	Chmu-methyl ester

Description	(S)-mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S)-mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S)-mchm5U can be used for RNA modification synthesis[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. van den Born E, et al. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. Nat Commun. 2011 Feb 1;2:172.