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397290-30-1

397290-30-1 structure
397290-30-1 structure
  • Name: ue1654
  • Chemical Name: N-[7-(Methylsulfanyl)[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl]- 2,2-diphenylacetamide
  • CAS Number: 397290-30-1
  • Molecular Formula: C23H17N3OS3
  • Molecular Weight: 447.59600
  • Create Date: 2016-04-03 12:12:19
  • Modify Date: 2025-09-18 11:21:33
  • Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].

Name N-[7-(Methylsulfanyl)[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl]- 2,2-diphenylacetamide
Description Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].
Related Catalog
References

[1]. Blättermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.

Molecular Formula C23H17N3OS3
Molecular Weight 447.59600
Exact Mass 447.05300
PSA 140.15000
LogP 7.04800
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport
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