20235-78-3

20235-78-3 structure

Name: thiouridine
Chemical Name: 2-Thiouridine
CAS Number: 20235-78-3
Molecular Formula: C₉H₁₂N₂O₅S
Molecular Weight: 260.267
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-09-21 18:52:49
Modify Date: 2025-08-26 16:37:36
2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs.

Name	2-Thiouridine
Synonyms	1-(β-D-Ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone 4(1H)-Pyrimidinone, 2,3-dihydro-1-β-D-ribofuranosyl-2-thioxo- 2-Thiouridine 2-thiouridine— thiouridine 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

21052-18-6

~90%

20235-78-3

Literature: El-Tayeb, Ali; Qi, Aidong; Mueller, Christa E. Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7076 - 7087

6974-32-9

~85%

20235-78-3

25030-30-2

~65%

20235-78-3

Literature: Robin, Aelig; Julienne, Karine; Meslin, Jean-Claude; Deniaud, David European Journal of Organic Chemistry, 2006 , # 3 p. 634 - 643

627812-08-2

20235-78-3

Literature: European Journal of Organic Chemistry, , # 3 p. 634 - 643

6984-55-0

20235-78-3

Literature: Journal of the Chemical Society, , p. 3028,3033

7408-41-5

20235-78-3

Literature: Journal of the Chemical Society, , p. 2294,2297

53337-88-5

13957-31-8

20235-78-3

Literature: Journal of Heterocyclic Chemistry, , vol. 17, p. 1601 - 1602

59495-20-4

13957-31-8

20235-78-3

Literature: Journal of Heterocyclic Chemistry, , vol. 17, p. 1601 - 1602

3868-21-1

20235-78-3

Literature: Journal of the Chemical Society, , p. 3028,3033