3608-58-0
- Name: 3'-Deoxyguanosine
- Chemical Name: 3'-deoxyguanosine
- CAS Number: 3608-58-0
- Molecular Formula: C10H13N5O4
- Molecular Weight: 267.24
- Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
- Create Date: 2018-07-16 20:21:12
- Modify Date: 2024-01-03 09:08:23
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3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 3'-deoxyguanosine |
|---|---|
| Synonyms |
9H-purin-6-ol, 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-
3'-Deoxy-D-guanosine MFCD00079149 3'-deoxyriboguanosine 3'-Deoxyguanosine 3'-deoxyguanosine monohydrate 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol 3'-deoxy-guanosine 3'-DG Guanosine, 3'-deoxy- |
| Description | 3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 725.5±70.0 °C at 760 mmHg |
| Melting Point | <300℃ (water ) |
| Molecular Formula | C10H13N5O4 |
| Molecular Weight | 267.24 |
| Flash Point | 392.6±35.7 °C |
| Exact Mass | 267.096741 |
| PSA | 140.01000 |
| LogP | -0.72 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.907 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934999090 |
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~99%
3608-58-0 |
| Literature: Bhan, Purshotam; Bhan, Anila; Hong, Mikung; Hartwell, John G.; Saunders, June M.; Hoke, GlennD Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1195 - 1199 |
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| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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| Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 |
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| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 22, # 5-8 p. 751 - 753 |
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| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 22, # 5-8 p. 751 - 753 |
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| Literature: Nucleosides and Nucleotides, , vol. 16, # 7-9 p. 1195 - 1199 |
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| Literature: Nucleosides and Nucleotides, , vol. 16, # 7-9 p. 1195 - 1199 |
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| Literature: Nucleosides and Nucleotides, , vol. 13, # 5 p. 1049 - 1058 |
| Precursor 9 | |
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| DownStream 2 | |
![N-[9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide structure](https://image.chemsrc.com/caspic/050/157025-66-6.png)
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |