Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3,4-Dehydro Cilostazol
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: 3,4-Dehydro Cilostazol
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

73963-62-9

73963-62-9 structure

73963-62-9 structure

Name: 3,4-Dehydro Cilostazol
Chemical Name: 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-1H-quinolin-2-one
CAS Number: 73963-62-9
Molecular Formula: C₂₀H₂₅N₅O₂
Molecular Weight: 367.44500
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-12-25 11:15:59
Modify Date: 2025-08-25 18:02:56
3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study[1].

Name	6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-1H-quinolin-2-one
Synonyms	3,4-dehydro-cilostazol UNII-5M77W4SPE0 QUI006

Description	3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease
In Vivo	3,4-Dehydro Cilostazol (OPC-13015; Oral; 1 mg/kg GLZ and 10 mg/kg CLZ) has a T1/2 of 3.94 hours, a Cmax of 1.39 μM and an AUC0-24 of 4.69 μg•h/ml. The plasma concentration time profiles of GLZ, CLZ & its active metabolite DCLZ are traceable up to 24 h, 12 h and 12 h respectively by oral administration at 1 mg/kg dose of GLZ and 10 mg/kg CLZ[1]. Animal Model: Male Wistar rats weighing 200 g[1] Dosage: 1 mg/kg Glipizide (GLZ) and 10 mg/kg Cilostazol (CLZ) (Pharmacokinetic Analysis) Administration: Oral Result: Had a T1/2 of 3.94 hours, a Cmax of 1.39 μM and an AUC0-24 of 4.69 μg•h/ml.
References	[1]. T R S Satheeshmanikandan, et al. Liquid Chromatography - Tandem Mass Spectrometry for the Simultaneous Quantitation of Glipizide, Cilostazol and Its Active Metabolite 3, 4-dehydro-cilostazol in Rat Plasma: Application for a Pharmacokinetic Study. Arzneimittelforschung. 2012 Sep;62(9):425-32.

Density	1.342g/cm3
Boiling Point	675.937ºC at 760 mmHg
Melting Point	179-180ºC
Molecular Formula	C₂₀H₂₅N₅O₂
Molecular Weight	367.44500
Flash Point	362.594ºC
Exact Mass	367.20100
PSA	85.69000
LogP	3.42150
Index of Refraction	1.676

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport

54197-66-9 structure

54197-66-9

73963-42-5 structure

73963-42-5

~0%

865792-18-3 structure

865792-18-3

73963-72-1 structure

73963-72-1

Detail

Literature: WO2006/22488 A1, ; Page/Page column 3 ;

19315-93-6 structure

19315-93-6

73963-42-5 structure

73963-42-5

~85%

73963-62-9 structure

73963-62-9

Literature: Heterocycles, , vol. 78, # 1 p. 189 - 195

Precursor 3
54197-66-9 73963-42-5 19315-93-6
DownStream 0

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