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12071-83-9

12071-83-9 structure
12071-83-9 structure
  • Name: propineb
  • Chemical Name: propineb
  • CAS Number: 12071-83-9
  • Molecular Formula: C5H8N2S4Zn
  • Molecular Weight: 289.77
  • Catalog: Chemical pesticide Fungicide Pesticide fungicide
  • Create Date: 2018-09-10 11:57:17
  • Modify Date: 2025-08-19 23:38:29
  • Propineb (Zinc propylenebis) is a compound widely used in fruit and vegetables cultures, due to its large spectrum of activity against fungal plant diseases[1].
Name propineb
Synonyms [[(1-Methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc
[Propylenebis(dithiocarbamato)]zinc
ZINC TRIFLUOROACETATE
trifluoro-acetic acid,zinc-trifluoroacetate
EINECS 235-134-0
Zinc 1,2-propanediyldicarbamodithioate
Zinc propane-1,2-diyldicarbamodithioate
Carbamodithioic acid, N,N'-(1-methyl-1,2-ethanediyl)bis-, zinc salt (1:1)
MFCD00055491
zinc rifluoroacetate
zinc,N-[1-(sulfidocarbothioylamino)propan-2-yl]carbamodithioate
Description Propineb (Zinc propylenebis) is a compound widely used in fruit and vegetables cultures, due to its large spectrum of activity against fungal plant diseases[1].
Related Catalog
In Vivo Propineb (Zinc propylenebis) has a moderate to low acute toxicity with a specific goitrogenic effect in rats. long-term exposure, oral or by inhalation is related to carcinogenicity, teratogenicity, malfunction of the reproductive system and malformation of their vitals[2].
References

[1]. Viviani B, et al. Dithiocarbamate propineb induces acetylcholine release through cytoskeletal actin depolymerization in PC12 cells. Toxicol Lett. 2008 Nov 10;182(1-3):63-8.

[2]. Kazos EA, et al. Determination of dithiocarbamate fungicide propineb and its main metabolite propylenethiourea in airborne samples. Chemosphere. 2007 Aug;68(11):2104-10.
Boiling Point 315.4ºC at 760 mmHg
Melting Point 160ºC
Molecular Formula C5H8N2S4Zn
Molecular Weight 289.77
Flash Point 144.5ºC
Exact Mass 287.886169
PSA 165.84000
LogP 1.76530

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZH4950000
CHEMICAL NAME :
Zinc, (N,N'-propylene-1,2-bis(dithiocarbamate))
CAS REGISTRY NUMBER :
12071-83-9
LAST UPDATED :
199409
DATA ITEMS CITED :
12
WISWESSER LINE NOTATION :
SUYS&MY1&1MYS&US &ZN-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>693 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2300 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2300 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1 gm/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2 gm/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
2600 mg/kg/5D (Intermittent)
REFERENCE :
PRKHDK Problemi na Khigienata. Problems in Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, Pl. Slaveikov 11, Sofia, Bulgaria) V.1- 1975- Volume(issue)/page/year: 4,151,1979
Personal Protective Equipment Eyeshields;Faceshields;Gloves
Hazard Codes N: Dangerous for the environment;
Risk Phrases 51/53
Safety Phrases 60-61
RIDADR UN3077 9/PG 3
RTECS ZH4950000
Packaging Group III
HS Code 2930200012
HS Code 2930200012
Summary 2930200012 iron(iii) dimethylcarbamodithioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%
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