537034-17-6
537034-17-6 structure
- Name: BML-210
- Chemical Name: bml-210
- CAS Number: 537034-17-6
- Molecular Formula: C20H25N3O2
- Molecular Weight: 339.431
- Catalog: Research Areas Cancer
- Create Date: 2016-04-21 10:22:28
- Modify Date: 2024-01-02 08:19:47
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BML-210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized.IC50 value: 5 μM[1]Target: HDAC4In vitro: Cell cycle analysis indicated that HeLa cell treatment with 20 and 30 μM concentration of BML-210 increased the proportion of cells in G0/G1 phase, and caused accumulation in subG1, indicating that the cells are undergoing apoptosis[2]. BML-210 inhibits the growth of NB4 cells in dose- and time-dependent manner[3].In vivo:
| Name | bml-210 |
|---|---|
| Synonyms |
BML-210
N'-(2-aminophenyl)-N-phenyloctanediamide N-(2-Aminophenyl)-N'-phenyloctanediamide Octanediamide, N-(2-aminophenyl)-N-phenyl- |
| Description | BML-210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized.IC50 value: 5 μM[1]Target: HDAC4In vitro: Cell cycle analysis indicated that HeLa cell treatment with 20 and 30 μM concentration of BML-210 increased the proportion of cells in G0/G1 phase, and caused accumulation in subG1, indicating that the cells are undergoing apoptosis[2]. BML-210 inhibits the growth of NB4 cells in dose- and time-dependent manner[3].In vivo: |
|---|---|
| Related Catalog | |
| Target |
HDAC4:MEF2 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 632.5±40.0 °C at 760 mmHg |
| Molecular Formula | C20H25N3O2 |
| Molecular Weight | 339.431 |
| Flash Point | 336.3±27.3 °C |
| Exact Mass | 339.194672 |
| PSA | 84.22000 |
| LogP | 2.58 |
| Appearance | white solid |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.633 |
| Storage condition | -20℃ |
| Hazard Statements | H413 |
|---|---|
| RIDADR | NONH for all modes of transport |