1007573-18-3

1007573-18-3 structure

Name: GSK-1521498
Chemical Name: N-[[2,6-difluoro-3-(1H-1,2,4-triazol-5-yl)phenyl]methyl]-2,3-dihydro-1H-inden-2-amine
CAS Number: 1007573-18-3
Molecular Formula: C₂₄H₂₀F₂N₄
Molecular Weight: 326.34300
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2016-03-04 00:02:29
Modify Date: 2024-01-02 17:58:25
GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].

Name	N-[[2,6-difluoro-3-(1H-1,2,4-triazol-5-yl)phenyl]methyl]-2,3-dihydro-1H-inden-2-amine
Synonyms	unii-w0utb622gk GSK-1521498

Description	GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	μ-opioid receptor[1]
References	[1]. Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92.