21913-98-4
21913-98-4 structure
- Name: 3'-Methoxydaidzein
- Chemical Name: 7,4'-dihydroxy-3'-methoxyisoflavone
- CAS Number: 21913-98-4
- Molecular Formula: C16H12O5
- Molecular Weight: 284.26
- Catalog: Natural product Flavonoids
- Create Date: 2016-03-30 04:16:42
- Modify Date: 2025-08-26 03:59:35
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3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].
| Name | 7,4'-dihydroxy-3'-methoxyisoflavone |
|---|---|
| Synonyms |
Isoflavone,4',7-dihydroxy-3'-methoxy
3'-Methoxydaidzein 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)chromen-4-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 4',7-dihydroxy-3'-methoxyisoflavone 7,4'-dihydroxy-3'-methoxy-isoflavone 7-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one |
| Description | 3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1]. |
|---|---|
| Related Catalog | |
| Target |
Nav1.3:505 nM (IC50) Nav1.7:181 nM (IC50) Nav1.8:397 nM (IC50) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 534.5±50.0 °C at 760 mmHg |
| Melting Point | 258-260℃ |
| Molecular Formula | C16H12O5 |
| Molecular Weight | 284.26 |
| Flash Point | 204.8±23.6 °C |
| Exact Mass | 284.068481 |
| PSA | 79.90000 |
| LogP | 2.54 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.669 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2914509090 |
| Precursor 9 | |
|---|---|
| DownStream 0 | |
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |