141318-62-9

141318-62-9 structure

Name: LY 293284
Chemical Name: 1-[(4R)-4-(dipropylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-6-yl]ethanone
CAS Number: 141318-62-9
Molecular Formula: C₁₉H₂₆N₂O
Molecular Weight: 298.42
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-01-16 01:41:20
Modify Date: 2025-08-21 08:28:48
LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].

Name	1-[(4R)-4-(dipropylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-6-yl]ethanone
Synonyms	Ethanone,1-(4-(dipropylamino)-1,3,4,5-tetrahydrobenz(cd)indol-6-yl)-,(R) 6-Acetyl-4-(di-n-propylamino)-1,3,4,5-tetrahydrobenz(c,d)indole C19H26N2O

Description	LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Marona-Lewicka D, et al. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl). 2004;172(4):415-421. [2]. Burak KW, et al. Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats. Brain Res. 2001;892(2):376-379.