1227923-29-6
1227923-29-6 structure
- Name: MK-7622
- Chemical Name: 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]b enzo[h]quinazolin-4(3H)-one
- CAS Number: 1227923-29-6
- Molecular Formula: C25H25N3O2
- Molecular Weight: 399.485
- Catalog: Signaling Pathways GPCR/G Protein mAChR
- Create Date: 2018-06-15 18:55:09
- Modify Date: 2025-08-25 09:50:07
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MK-7622 is a muscarinic M1 receptor positive allosteric modulator.Target: M1 receptorMK-7622 is useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders.
| Name | 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]b enzo[h]quinazolin-4(3H)-one |
|---|---|
| Synonyms |
3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4(3H)-one
(S)-3-(1-AMINOETHYL)BENZENAMINE 3-[(1S)-1-azanylethyl]aniline Benzo[h]quinazolin-4(3H)-one, 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]- (S)-1-(3-Aminophenyl)-1-aminoethane 3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one MK-7622 |
| Description | MK-7622 is a muscarinic M1 receptor positive allosteric modulator.Target: M1 receptorMK-7622 is useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 643.0±65.0 °C at 760 mmHg |
| Molecular Formula | C25H25N3O2 |
| Molecular Weight | 399.485 |
| Flash Point | 342.7±34.3 °C |
| Exact Mass | 399.194672 |
| PSA | 68.01000 |
| LogP | 3.37 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.687 |
|
~%
1227923-29-6 |
| Literature: WO2012/47702 A1, ; Page/Page column 39 ; WO 2012/047702 A1 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |