Top Suppliers:I want be here
Related CAS#:
11000-17-2 9034-50-8
43157-23-9 64158-84-5
34223-44-4 3397-23-7
50-57-7 113-80-4
113-79-1 103529-95-9
1189766-80-0 1189766-82-2
1189766-84-4 1189766-89-9
1189766-99-1 1189767-00-7
1189766-93-5 1189766-98-0
1189767-06-3 1189767-13-2

11000-17-2

11000-17-2 structure
11000-17-2 structure
  • Name: Vasopressin
  • Chemical Name: Vasopressin
  • CAS Number: 11000-17-2
  • Molecular Formula: C43H67N15O12S2
  • Molecular Weight: 1050.22000
  • Catalog: API Hormone and endocrine-regulating drugs Pituitary hormone
  • Create Date: 2018-09-02 13:36:26
  • Modify Date: 2025-08-23 19:29:27
  • Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors[1][2][3].
Name Vasopressin
Synonyms pituitrin
EINECS 200-050-5
VASOPRESSIN ACETATE
MFCD03839092
vasophysin
leiormone
tonephin
VASOPRASSIN
adh(hormone)
pitressin
Description Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro AVP (0.01 nM-1 μM) induces Ca2+ increase in Chinese hamster ovary cells expressing rat or human V1b receptors[2].
In Vivo Vasopressin (0.03-0.3 μg/kg; i.p.) potentiates corticotropin release provoked by exogenous corticoliberin and increases corticotropin secretion subsequent to body water loss[2]. Vasopressin (0.001-0.1 mg/kg; i.p.) potently increases adjacent lying, where rats meeting for the first time lie passively next to each other[3].
References

[1]. Baribeau DA, et, al. Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits. Front Neurosci. 2015 Sep 24;9:335.

[2]. Ramos L, et, al. Acute prosocial effects of oxytocin and vasopressin when given alone or in combination with 3,4-methylenedioxymethamphetamine in rats: involvement of the V1A receptor. Neuropsychopharmacology. 2013 Oct;38(11):2249-59.

[3]. Gal CSL, et, al. Characterization of (2S,4R)-1-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a selective and orally active vasopressin V1b receptor antagonist. J Pharmacol Exp Ther. 2002 Mar;300(3):1122-30.
Molecular Formula C43H67N15O12S2
Molecular Weight 1050.22000
Exact Mass 1049.45000
PSA 505.74000
LogP 1.50910

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YW8200000
CHEMICAL NAME :
Vasopressin
CAS REGISTRY NUMBER :
11000-17-2
LAST UPDATED :
199504

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 iu/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,415,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4661 No. of Facilities: 114 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 3153 (estimated) No. of Female Employees: 1738 (estimated)
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:11000-17-2 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 11000-17-2 | Chemsrc address: https://www.chemsrc.com/en/baike/445386.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved