321-55-1

321-55-1 structure

Name: Haloxon
Chemical Name: Bis(2-chloroethyl) 3-chloro-4-methyl-2-oxo-2H-chromen-7-yl phosph ate
CAS Number: 321-55-1
Molecular Formula: C₁₄H₁₄Cl₃O₆P
Molecular Weight: 415.59000
Catalog: Signaling Pathways Anti-infection Parasite
Create Date: 2017-10-23 23:47:46
Modify Date: 2024-01-04 11:48:52
Haloxon is an organophosphorus anthelmintic once used against nematodes of the abomasum and small intestine in ruminants.

Name	Bis(2-chloroethyl) 3-chloro-4-methyl-2-oxo-2H-chromen-7-yl phosph ate
Synonyms	2-Ethylhexyl 4,4-bis(3-butoxy-3-oxopropyl)-10-ethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate di(2-butoxycarbonylethyl)tin S,S'-bis-(2-ethylhexyl thioglycolate) Di-(2-chlorethyl)-3-chloro-4-methylcoumarin-7-yl-phosphat 8-Oxa-3,5-dithia-4-stannatetradecanoicacid,4,4-bis(3-butoxy-3-oxopropyl)-10-ethyl-7-oxo-,2-ethylhexyl ester Haloxon

Description	Haloxon is an organophosphorus anthelmintic once used against nematodes of the abomasum and small intestine in ruminants.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Others

Density	1.5g/cm3
Boiling Point	504.6ºC at 760 mmHg
Molecular Formula	C₁₄H₁₄Cl₃O₆P
Molecular Weight	415.59000
Flash Point	438.8ºC
Exact Mass	413.95900
PSA	84.78000
LogP	4.75250
Index of Refraction	1.561
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN5250000

CHEMICAL NAME :: Coumarin, 3-chloro-7-hydroxy-4-methyl-, bis(2-chloroethyl) phosphate

CAS REGISTRY NUMBER :: 321-55-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C14-H14-Cl3-O6-P

MOLECULAR WEIGHT :: 415.60

WISWESSER LINE NOTATION :: T66 BOVJ DG E1 IOPO&O2GO2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >6 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: >7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 763 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 10 mg/L

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 10,143,1982 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H332-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
RIDADR	NONH for all modes of transport
RTECS	GN5250000
HS Code	2932209090

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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