5274-63-5
5274-63-5 structure
- Name: Tetraethylene glycol monohexadecyl ether
- Chemical Name: 2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethanol
- CAS Number: 5274-63-5
- Molecular Formula: C24H50O5
- Molecular Weight: 418.65100
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-03-20 08:00:00
- Modify Date: 2024-01-05 14:45:08
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Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethanol |
|---|---|
| Synonyms |
CETETH-4
Tetraethylene glycol monohexadecyl ether Hexadecyltetraglycol C16E4 C16E4,Hexadecyl tetraethylene glycol ether,Hexadecyltetraglycol polyoxyethylene 4 cetyl ether Hexadecyl tetraethylene glycol ether |
| Description | Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 37-38ºC |
|---|---|
| Molecular Formula | C24H50O5 |
| Molecular Weight | 418.65100 |
| Exact Mass | 418.36600 |
| PSA | 57.15000 |
| LogP | 5.52640 |
| Safety Phrases | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 2909499000 |
| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |