303-48-0
303-48-0 structure
- Name: Didemethylclomipramine
- Chemical Name: n-desmethylclomipramine hydrochloride
- CAS Number: 303-48-0
- Molecular Formula: C18H22Cl2N2
- Molecular Weight: 337.28700
- Create Date: 2018-03-24 08:00:00
- Modify Date: 2025-08-20 22:40:51
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Didemethylclomipramine (Norclomipramine, N-Desmethylcomipramine) is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine.
| Name | n-desmethylclomipramine hydrochloride |
|---|---|
| Synonyms |
Demethylchlorimipramine
[3-(3-chloro-10,11-dihydro-dibenzo[b,f]azepin-5-yl)-propyl]-methyl-amine N-Desmethylclomipramine HCl Norclomipramine n-desmethylclomipramine Chlordesipramine desmethylclomipramine N-Demethylclomipramine N-Desmethylchlomipramine Desmethylchlomipramine Demethylchlomipramine Desmethylchlorimipramine |
| Density | 1.129g/cm3 |
|---|---|
| Boiling Point | 439.5ºC at 760mmHg |
| Molecular Formula | C18H22Cl2N2 |
| Molecular Weight | 337.28700 |
| Flash Point | 219.6ºC |
| Exact Mass | 336.11600 |
| PSA | 15.27000 |
| LogP | 5.44410 |
| Index of Refraction | 1.583 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22 |
| Safety Phrases | 36 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
|
~%
303-48-0 |
| Literature: Chaudhuri, Naba K.; Servando, Ofelia; Markus, Bohdan; Galynker, Igor; Sung, Ming-Sang Journal of the Indian Chemical Society, 1985 , vol. 62, # 11 p. 899 - 903 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |