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319-85-7

319-85-7 structure
319-85-7 structure
  • Name: β-Hexachlorocyclohexane
  • Chemical Name: β-hexachlorocyclohexane
  • CAS Number: 319-85-7
  • Molecular Formula: C6H6Cl6
  • Molecular Weight: 290.830
  • Create Date: 2018-08-16 17:11:44
  • Modify Date: 2024-01-03 12:54:25
Name β-hexachlorocyclohexane
Synonyms Hexachlorocyclohexane-β
beta-hexachlorocyclohexane
ENT 9,233
EINECS 200-659-6
b-BHC
b-Hexachlorocyclohexane
1-α,2-β,3-α,4-β,5-α,6-β-Hexachlorocyclohexane
b-Hexachlorobenzene
Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1α,2β,3α,4β,5α,6β)-
β-BHC
β-lindane
(1a,2b,3a,4b,5a,6b)-1,2,3,4,5,6-Hexachlorocyclohexane
b-Lindane
trans-a-Benzenehexachloride
betaisomer
b-HCH
β-benzene hexachloride
β-HCH
β-HEXACHLOROBENZENE
1a,2b,3a,4b,5a,6b-Hexachlorocyclohexane
(1r,2r,3r,4r,5r,6r)-1,2,3,4,5,6-Hexachlorocyclohexane
1,2,3,4,5,6-Hexachlorocyclohexane b-Isomer
b-Hexachloran
Density 1.6±0.1 g/cm3
Boiling Point 288.0±0.0 °C at 760 mmHg
Melting Point ≥300ºC
Molecular Formula C6H6Cl6
Molecular Weight 290.830
Flash Point 157.5±23.9 °C
Exact Mass 287.860077
LogP 3.99
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.533

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GV4375000
CHEMICAL NAME :
Cyclohexane, 1,2,3,4,5,6-hexachloro-, beta-isomer
CAS REGISTRY NUMBER :
319-85-7
BEILSTEIN REFERENCE NO. :
1907338
LAST UPDATED :
199710
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C6-H6-Cl6
MOLECULAR WEIGHT :
290.82
WISWESSER LINE NOTATION :
L6TJ AG BG CG DG EG FG BETA

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ALLVAR Alimentation et la Vie. (Societe Scientifique d'Hygiene Alimentaire, 16, rue de l'Estrapade, 75005 Paris, France) V.39- 1951- Volume(issue)/page/year: 43,-,1955
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 22,273,1959 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
672 mg/kg/2W-C
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 41,531,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22750 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,697,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8736 mg/kg/26W-C
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Related to Chronic Data - death
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 100,59,1950
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1989 mg/kg/30D-C
TOXIC EFFECTS :
Peripheral Nerve and Sensation - recording from peripheral motor nerve
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 27,704,1981
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 gm/kg/30D-C
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in other cell count (unspecified) Immunological Including Allergic - decrease in cellular immune response
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 11,293,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
2250 mg/kg/90D-I
TOXIC EFFECTS :
Liver - fatty liver degeneration Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 70,85P,1974 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,433,1973 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
672 mg/kg/
SEX/DURATION :
male 2 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 41,531,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,195,1979 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 0.5 mg/m3;Skin JAN 1993 OEL-GERMANY:TWA 0.5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.5 mg/m3;Skin JAN 1993
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319-H336-H412
Supplemental HS Repeated exposure may cause skin dryness or cracking.
Precautionary Statements P210-P273-P280-P304 + P340 + P312-P337 + P313-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F,T,N
Risk Phrases 11-23/24/25-39/23/24/25-50/53-40-25-21
Safety Phrases S7;S16;S45;S60;S61;S36/S37
RIDADR UN1230 3/PG 2
RTECS GV4375000
319-84-6 structure

319-84-6

~51%

119911-69-2 structure

119911-69-2
319-86-8 structure

319-86-8
319-85-7 structure

319-85-7
Literature: Wu; Xu; Schramm; Kettrup Chemosphere, 1997 , vol. 35, # 9 p. 1887 - 1894
71-43-2 structure

71-43-2

~%

319-85-7 structure

319-85-7
Literature: Zeitschrift fuer Naturforschung, , vol. 4 b, p. 133,135 Chemistry and Industry (London, United Kingdom), , p. 314,316
319-86-8 structure

319-86-8

~%

58-89-9 structure

58-89-9
319-85-7 structure

319-85-7

41992-55-6 structure

41992-55-6
Detail
Literature: Journal of Organic Chemistry, , vol. 48, # 12 p. 1966 - 1970
319-84-6 structure

319-84-6

~%

319-86-8 structure

319-86-8
58-89-9 structure

58-89-9
319-85-7 structure

319-85-7

Detail
Literature: Journal of Organic Chemistry, , vol. 48, # 12 p. 1966 - 1970
58-89-9 structure

58-89-9
7705-08-0 structure

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~%

319-86-8 structure

319-86-8
319-85-7 structure

319-85-7

Detail
Literature: Journal of the American Chemical Society, , vol. 75, p. 1768
319-84-6 structure

319-84-6
7705-08-0 structure

7705-08-0

~%

6108-10-7 structure

6108-10-7
319-86-8 structure

319-86-8
Detail
Literature: Journal of the American Chemical Society, , vol. 75, p. 1768
58-89-9 structure

58-89-9
7727-15-3 structure

7727-15-3

~%

319-86-8 structure

319-86-8
319-85-7 structure

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Detail
Literature: DE953342 , ;
7446-70-0 structure

7446-70-0
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319-86-8 structure

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Detail
Literature: DE953342 , ; US2749373 , ;
7647-01-0 structure

7647-01-0
7446-70-0 structure

7446-70-0
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319-86-8 structure

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Detail
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title: CAS No. 319-85-7 | Chemsrc address: https://www.chemsrc.com/en/baike/404013.html

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