89-82-7

89-82-7 structure

Name: Pulegone
Chemical Name: (+)-pulegone
CAS Number: 89-82-7
Molecular Formula: C₁₀H₁₆O
Molecular Weight: 152.233
Catalog: Flavors and spices Synthetic spice Ketone fragrance Aromatic ketone
Create Date: 2018-02-25 08:00:00
Modify Date: 2024-01-04 20:30:37
Pulegone, the major chemical constituent of Calamintha nepeta (L.) Savi essential oil which is an aromatic herb with a mint-oregano flavor, is one of avian repellents[1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations[2].

Name	(+)-pulegone
Synonyms	(5R)-5-methyl-2-(methylethylidene)cyclohexan-1-one (5R)-2-Isopropylidéne-5-méthylcyclohexanone (R)-Pulegone Cyclohexanone, 5-methyl-2- (1-methylethylidene)-, (R)- PULEGON MFCD00063000 PULEGONE,TECH 2-isopropylidene-5-methylcyclohexan-1-one p-Menth-4(8)-en-3-one, (R)-(+)- EINECS 201-943-2 (5R)-5-Methyl-2-(2-propanyliden)cyclohexanon Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (5R)- (+)-(R)-Pulegone D-PULEGONE R-(+)-Pulegone Pulegone,(d) (1R)-(+)-pulegone (5R)-2-Isopropylidene-5-methylcyclohexanone (+)-Pulegone R-(+)-p-Menth-4(8)-en-3-one FEMA 2963 Pulegone

Description	Pulegone, the major chemical constituent of Calamintha nepeta (L.) Savi essential oil which is an aromatic herb with a mint-oregano flavor, is one of avian repellents[1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Others
References	[1]. Božović M, et al. Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry. Molecules. 2017 Feb 14;22(2). [2]. Majikina A, et al. Involvement of nociceptive transient receptor potential channels in repellent action of pulegone. Biochem Pharmacol. 2018 May;151:89-95.

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section

REFERENCE :: COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 236,633,1953

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H302-H351-H412
Precautionary Statements	P273-P301 + P312 + P330
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S23-S24/25
RIDADR	2810
WGK Germany	3
RTECS	OT0261000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2914299000

HS Code	2914299000
Summary	2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%