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71-27-2

71-27-2 structure
71-27-2 structure
Name succinylcholine chloride (anhydrous)
Synonyms 2,2'-[(1,4-Dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride
2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethylethanaminium] Dichloride
2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride
Succinylcholine Chloride
Succinic Acid Bis[b-dimethylaminoethyl] Ester Dimethochloride
Suxamethonium chloride
QUELICIN
Succinylcholine dichloride
Succinyldicholine chloride
MFCD00038725
succinylcholine chloride (anhydrous)
Succinylcholine Chloride Dihydrate
Listenon
Succinic acid bis[β-dimethylaminoethyl] ester dimethochloride
Ultrapal Chloride
EINECS 200-747-4
Suxamethoniumchloride
Ethanaminium, 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)
Suxamethonium dichloride
Bis[2-dimethylaminoethyl]succinate Bis[methochloride]
Succinyldicholine dichloride
2,2'-[(1,4-Dioxobutan-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)dichlorid
trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium,dichloride
Melting Point 164ºC
Molecular Formula C14H30Cl2N2O4
Molecular Weight 361.305
Exact Mass 360.158264
PSA 52.60000
Storage condition Refrigerator
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GA2360000
CAS REGISTRY NUMBER :
71-27-2
LAST UPDATED :
199706
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C14-H30-N2-O4.2Cl
MOLECULAR WEIGHT :
361.36
WISWESSER LINE NOTATION :
1K1&1&2OV2VO2K1&1&1 &Q 2 &G 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
1429 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - changes in potassium
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
7 mg/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - changes in potassium Cardiac - arrhythmias (including changes in conduction)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
430 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
240 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - altered sleep time (including change in righting reflex) Behavioral - rigidity (including catalepsy)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
2500 ug/kg
REFERENCE :
MSCREJ Medical Science Research. (Elsevier Applied Science Pub. Ltd., Crown House, Linton Rd., Barking, Essex IG11 8JU, UK) V.15- 1987- Volume(issue)/page/year: 20,759,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84013 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 400 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84013 No. of Facilities: 207 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 10334 (estimated) No. of Female Employees: 9106 (estimated)
Safety Phrases 7-8
RIDADR UN 3249
RTECS GA2360000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2923900090
33109-58-9 structure

33109-58-9

67-48-1 structure

67-48-1

~88%

71-27-2 structure

71-27-2

Literature: NEON LABORATORIES LTD.; DALVI, Mahesh, Bhagoji; KENNY, Rajesh, Shashikant; CHINCHKAR, Dattatray, Krishna Patent: WO2014/24207 A1, 2014 ; Location in patent: Page/Page column 8 ;
83254-75-5 structure

83254-75-5

67-48-1 structure

67-48-1

~87%

71-27-2 structure

71-27-2

Literature: NEON LABORATORIES LTD.; DALVI, Mahesh, Bhagoji; KENNY, Rajesh, Shashikant; CHINCHKAR, Dattatray, Krishna Patent: WO2014/24207 A1, 2014 ; Location in patent: Page/Page column 8 ;
19249-04-8 structure

19249-04-8

~92%

71-27-2 structure

71-27-2

Literature: SEQUENT SCIENTIFIC LIMITED; MANJATHURU, Mahalinga; MAYEKAR, Anil Narayan; VASUDEVA, Pejakala Kakrannaya; ARULMOLI, Thangavel; DAS, Gautam Kumar Patent: US2014/100385 A1, 2014 ; Location in patent: Page/Page column ;
67-48-1 structure

67-48-1

543-20-4 structure

543-20-4

~%

71-27-2 structure

71-27-2

Literature: Gazzetta Chimica Italiana, , vol. 79, p. 130
925-17-7 structure

925-17-7

75-50-3 structure

75-50-3

~%

71-27-2 structure

71-27-2

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <4>3, p. 259,272 Acad. romine Stud. Cerc. Biochim., , vol. 1, p. 167,169
HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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