| Name | Aristolochic acid I sodium salt |
|---|---|
| Synonyms |
EINECS 233-463-4
sodium,8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylate |
| Description | Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a prodrug that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts. |
|---|---|
| Related Catalog |
| Boiling Point | 615.5ºC at 760 mmHg |
|---|---|
| Molecular Formula | C17H10NNaO7 |
| Molecular Weight | 363.25400 |
| Flash Point | 326ºC |
| Exact Mass | 363.03500 |
| PSA | 113.64000 |
| LogP | 2.52520 |
| Vapour Pressure | 5.24E-16mmHg at 25°C |
| Water Solubility | H2O: 50 mg/mL |
| Symbol |
GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331-H351 |
| Precautionary Statements | Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Phrases | R23/24/25 |
| Safety Phrases | S22;S45;S36/S37/S39 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | SF8281000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |