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13345-50-1

13345-50-1 structure
13345-50-1 structure
  • Name: PROSTAGLANDIN A2
  • Chemical Name: prostaglandin A2
  • CAS Number: 13345-50-1
  • Molecular Formula: C20H30O4
  • Molecular Weight: 334.450
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-07-17 13:11:48
  • Modify Date: 2024-01-02 10:19:27
  • Prostaglandin A2 (PGA2), a human endogenous metabolite of PGE2, is an antitumor agent. Prostaglandin A2 induces p53-dependent Apoptosis. Prostaglandin A2 also has antiviral activity[1][2][3].
Name prostaglandin A2
Synonyms PROSTAGLANDINS A2
Prostaglandin A
Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5E,13E,15S)-
Prostaglandin A2 solution
(5E,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid
Prostaglandin A2
MFCD00077859
PGA2
MEDULLIN
Density 1.1±0.1 g/cm3
Boiling Point 515.3±50.0 °C at 760 mmHg
Molecular Formula C20H30O4
Molecular Weight 334.450
Flash Point 279.6±26.6 °C
Exact Mass 334.214417
PSA 74.60000
LogP 3.25
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.555

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UK8050000
CHEMICAL NAME :
Prostaglandin A(sup 2)
CAS REGISTRY NUMBER :
13345-50-1
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C20-H30-O4
MOLECULAR WEIGHT :
334.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
93 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,460,1973 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
5 mg/kg
SEX/DURATION :
female 16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 1,191,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
10 mg/kg
SEX/DURATION :
female 16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion
REFERENCE :
PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 1,191,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
10 mg/kg
SEX/DURATION :
female 16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,295,1972 *** REVIEWS *** TOXICOLOGY REVIEW CSPEAX Cosmetics and Perfumery. (Oak Park, IL) V.88-90, 1973-75. For publisher information, see CTOIDG. Volume(issue)/page/year: 90(12),28,1975
Hazard Codes F: Flammable;Xi: Irritant;
Risk Phrases R11
Safety Phrases S26
RIDADR UN 1231 3/PG 2

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