369358-07-6
369358-07-6 structure
- Name: A-357300
- Chemical Name: N'-[(2S,3R)-3-Amino-2-hydroxy-5-(isopropylsulfanyl)pentanoyl]-3-c hlorobenzohydrazide hydrochloride (1:1) (non-preferred name)
- CAS Number: 369358-07-6
- Molecular Formula: C15H23Cl2N3O3S
- Molecular Weight: 396.33200
- Create Date: 2016-02-29 21:08:16
- Modify Date: 2025-09-01 09:50:05
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A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM, does not inhibit MetAP1 or leucine aminopeptidases at 10 uM.
| Name | N'-[(2S,3R)-3-Amino-2-hydroxy-5-(isopropylsulfanyl)pentanoyl]-3-c hlorobenzohydrazide hydrochloride (1:1) (non-preferred name) |
|---|
| Molecular Formula | C15H23Cl2N3O3S |
|---|---|
| Molecular Weight | 396.33200 |
| Exact Mass | 395.08400 |
| PSA | 136.73000 |
| LogP | 4.23830 |