4429-63-4

4429-63-4 structure

Name: Tabersonine
Chemical Name: tabersonine
CAS Number: 4429-63-4
Molecular Formula: C₂₁H₂₄N₂O₂
Molecular Weight: 336.427
Catalog: Natural product Alkaloid
Create Date: 2018-08-10 10:20:30
Modify Date: 2025-08-20 18:21:13
Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI/ARDS[1].

Name	tabersonine
Synonyms	EINECS 224-615-0 (-)-Tabersonine TABERSONINE Methyl (5α,19α)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate methyl 2,3,6,7-tetradehydro-5α,12β,19α-aspidospermidine-3-carboxylate Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5α,19α)-

Description	Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI/ARDS[1].
Related Catalog	Signaling Pathways >> Others >> Others
References	[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.

CHEMICAL NAME :: Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetrahydro-, methyl ester, (5-alpha,12-beta, 19-alpha)-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 13,123,1955

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport