- BioBioPha
- China
- Product Name: Phillyrin
- Price: ￥Inquiry/50mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Phillyrin
- Price: ￥198.0/20mg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Forsythin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
487-41-2
487-41-2 structure
- Name: Phillyrin
- Chemical Name: forsythin
- CAS Number: 487-41-2
- Molecular Formula: C27H34O11
- Molecular Weight: 534.552
- Catalog: Biochemical Chinese herbal medicine ingredients
- Create Date: 2018-06-28 10:58:24
- Modify Date: 2024-01-02 14:13:41
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Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities[1].
| Name | forsythin |
|---|---|
| Synonyms |
β-D-Glucopyranoside, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl
Pillyrin Chionanthin 4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-D-glucopyranoside PHILLYRIN Phillyroside phyllyrin [1S-(1a,3aa,4b,6aa)]-4-[4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl-b-D-glucopyranoside |
| Description | Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities[1]. |
|---|---|
| Related Catalog | |
| Target |
CYP1A2; CYP2D1[1] |
| In Vitro | Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells[1]. Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes[1]. RT-PCR[1] Cell Line: Human HepG2 hepatocyte cells Concentration: 1 μM; 2.5 μM; 5 μM Incubation Time: 24 hours Result: Reduced FAS and SREBP-1c mRNA expression. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 730.4±60.0 °C at 760 mmHg |
| Molecular Formula | C27H34O11 |
| Molecular Weight | 534.552 |
| Flash Point | 395.5±32.9 °C |
| Exact Mass | 534.210083 |
| PSA | 145.53000 |
| LogP | 0.08 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.596 |
| Hazard Codes | C |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29389090 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
