114420-66-5
114420-66-5 structure
- Name: Regaloside A
- Chemical Name: [(2S)-2-hydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] (E)-3-(4-hydroxyphenyl)prop-2-enoate
- CAS Number: 114420-66-5
- Molecular Formula: C18H24O10
- Molecular Weight: 400.37700
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2016-11-24 19:47:52
- Modify Date: 2024-01-09 12:13:28
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Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity[1].
| Name | [(2S)-2-hydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] (E)-3-(4-hydroxyphenyl)prop-2-enoate |
|---|---|
| Synonyms | Regaloside A |
| Description | Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity[1]. |
|---|---|
| Related Catalog | |
| Target |
p65 |
| In Vitro | Regaloside A (50 μg/mL; 2 hours) inhibits the expression of iNOS to 70.3 decreasing COX-2 expression to 131.6 in Raw 264.7 cells treated with LPS (1 μg/ml; pretreatment for 15 min). Regaloside A decreases the ratio of p-p65/p-65 to 40.7[1]. Regaloside A (50 μg/mL; pretreatment for 2 hours) decreases the expression of VCAM-1 to 48.6 in HASMCs with TNF-a (10 ng/ml; for 12 h)[1]. |
| References |
| Density | 1.51g/cm3 |
|---|---|
| Boiling Point | 729.1ºC at 760mmHg |
| Molecular Formula | C18H24O10 |
| Molecular Weight | 400.37700 |
| Flash Point | 260.7ºC |
| Exact Mass | 400.13700 |
| PSA | 166.14000 |
| Vapour Pressure | 2.58E-22mmHg at 25°C |
| Index of Refraction | 1.635 |
| Storage condition | -20℃ |
| Precursor 0 | |
|---|---|
| DownStream 2 | |
