Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Methyl p-coumarate
Price: ￥348.0/25g ￥118.0/5g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Methyl p-coumarate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl 4-hydroxycinnamate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Methyl 4-hydroxycinnamate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

3943-97-3

3943-97-3 structure

Name: Methyl p-coumarate
Chemical Name: Methyl 4-hydroxycinnamate
CAS Number: 3943-97-3
Molecular Formula: C₁₀H₁₀O₃
Molecular Weight: 178.185
Catalog: Flavors and spices Synthetic spice Aromatic cinnamic acid, esters and derivatives
Create Date: 2018-02-20 08:00:00
Modify Date: 2024-01-02 16:52:20
Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens[1][2].

Name	Methyl 4-hydroxycinnamate
Synonyms	2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester p-Hydroxycinnamic acid methyl ester methyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (2E)- Cinnamic acid, p-hydroxy-, methyl ester EINECS 223-531-1 Methyl 3-(4-hydroxyphenyl)acrylate Methyl-4-hydroxy cinnamate Methyl (2E)-3-(4-hydroxyphenyl)acrylate Methyl 4-hydroxycinnamate MFCD00157167 2-Propenoic acid, 3- (4-hydroxyphenyl)-, methyl ester methyl trans-p-hydroxycinnamate

Description	Methyl p-coumarate (Methyl 4-hydroxycinnamate), an esterified derivative of p-Coumaric acid (pCA), is isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Kubo I, et, al. Methyl p-coumarate, a melanin formation inhibitor in B16 mouse melanoma cells. Bioorg Med Chem. 2004 Oct 15;12(20):5349-54. [2]. Yuan S, et, al. Defense Responses, Induced by p-Coumaric Acid and Methyl p-Coumarate, of Jujube ( Ziziphus jujuba Mill.) Fruit against Black Spot Rot Caused by Alternaria alternate. J Agric Food Chem. 2019 Mar 13;67(10):2801-2810.

Density	1.2±0.1 g/cm3
Boiling Point	306.6±17.0 °C at 760 mmHg
Melting Point	144-145ºC
Molecular Formula	C₁₀H₁₀O₃
Molecular Weight	178.185
Flash Point	132.8±13.7 °C
Exact Mass	178.062988
PSA	46.53000
LogP	1.64
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.593

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: Methyl 4-hydroxycinnamate
Synonyms:

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Methyl 4-hydroxycinnamate
CAS number:3943-97-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C10H10O3
Molecular weight:178.2

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

Hazard Codes	Xi
HS Code	2918290000

Precursor 8
67-56-1 7400-08-0 106-41-2 292638-85-8
55226-78-3 84184-51-0 149-73-5 74-88-4
DownStream 10
107019-92-1 501-98-4 501-97-3 20649-40-5
103-26-4 123-08-0 99-76-3 2373-79-7
62718-63-2 5597-50-2

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

3943-97-3	3901-07-3
55226-78-3	426207-35-4
107140-61-4	89278-88-6
934-72-5	5925-57-5
37773-35-6	34224-28-7