Name | 7-fluoro-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide |
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Synonyms |
FD5015
Sodium Channel inhibitor 1 |
Description | Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment. IC50 Value: 0.16 uM ( Na v1.7, V hold-90mV); 0.41 uM (Na v1.7, V hold-90mV) [1]Target: Na v1.7Sodium Channel inhibitor1 demonstrated concentration-dependent efficacy in preclinical behavioral pain models. |
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Related Catalog | |
References |
Molecular Formula | C24H19F4N3O3 |
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Molecular Weight | 473.42000 |
Exact Mass | 473.13600 |
PSA | 75.02000 |
LogP | 4.95350 |
Storage condition | 2-8℃ |