Name | (E)-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-3-[2-piperidin-1-yl-6-(trifluoromethyl)pyridin-3-yl]prop-2-enamide |
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Synonyms |
amg 0347
unii-cd7l9290qr |
Description | AMG0347 is a transient receptor potential type V1 receptor antagonist. AMG0347 inhibits activation of the rat TRPV1 channel by heat (IC50 = 0.2 nm), protons (IC50= 0.8 nm), or capsaicin (IC50 = 0.7 nm)[1]. |
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Related Catalog | |
References |
Molecular Formula | C24H26F3N3O2 |
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Molecular Weight | 445.47700 |
Exact Mass | 445.19800 |
PSA | 68.95000 |
LogP | 5.30670 |