247580-43-4

247580-43-4 structure

Name: SB 328437
Chemical Name: methyl (2S)-2-(naphthalene-1-carbonylamino)-3-(4-nitrophenyl)propanoate
CAS Number: 247580-43-4
Molecular Formula: C₂₁H₁₈N₂O₅
Molecular Weight: 378.37800
Catalog: Signaling Pathways GPCR/G Protein CCR
Create Date: 2017-06-07 23:19:52
Modify Date: 2025-08-21 10:08:26
SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM[1].

Name	methyl (2S)-2-(naphthalene-1-carbonylamino)-3-(4-nitrophenyl)propanoate
Synonyms	L-Phenylalanine,N-(1-naphthalenylcarbonyl)-4-nitro-,methyl ester (S)-Methyl-2-naphthoylamino-3-(4-nitrophenyl)propionate N-(1-NAPHTHALENYLCARBONYL)-4-NITRO-L-PHENYLALANINE METHYL ESTER L-Phenylalanine (N-(1-naphthalenylcarbonyl)-4-nitro

Description	SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Inflammation/Immunology
Target	CCR3:4.5 nM (IC50)
References	[1]. White JR, et al. Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration. J Biol Chem. 2000 Nov 24;275(47):36626-31.