DC Chemicals Limited
China
Product Name: (2S)-6-Prenylnaringenin
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

68236-13-5

68236-13-5 structure

68236-13-5 structure

Name: (2S)-6-Prenylnaringenin
Chemical Name: 6-prenylnaringenin
CAS Number: 68236-13-5
Molecular Formula: C₂₀H₂₀O₅
Molecular Weight: 340.37000
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2016-09-26 15:04:03
Modify Date: 2024-01-08 19:16:54
(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].

Name	6-prenylnaringenin
Synonyms	YS03 6-Prenylnaringenin 5,7,4'-Trihydroxy-6-prenylflavanone (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

Description	(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
In Vitro	(2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively[1].
References	[1]. Ali Y Benkherouf, et al. Hops Compounds Modulatory Effects and 6-prenylnaringenin Dual Mode of Action on GABA AReceptors. Eur J Pharmacol. 2020 Apr 15;873:172962.

Density	1.314±0.06 g/cm3
Molecular Formula	C₂₀H₂₀O₅
Molecular Weight	340.37000
Exact Mass	340.13100
PSA	86.99000
LogP	4.01860
Storage condition	2-8°C
Water Solubility	Insuluble (9.2E-3 g/L) (25 ºC)

RIDADR	NONH for all modes of transport