438226-89-2

438226-89-2 structure

Name: ReAsH-EDT2
Chemical Name: 4,6-bis(1,3,2-dithiarsolan-2-yl)-7-hydroxyphenoxazin-3-one
CAS Number: 438226-89-2
Molecular Formula: C₁₆H₁₃As₂NO₃S₄
Molecular Weight: 545.38300
Catalog: Research Areas Others
Create Date: 2016-04-06 09:20:48
Modify Date: 2025-08-25 10:31:24
ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].

Name	4,6-bis(1,3,2-dithiarsolan-2-yl)-7-hydroxyphenoxazin-3-one
Synonyms	Lumio Red ReAsH-EDT2 3H-Phenoxazin-3-one,4,6-di-1,3,2-dithiarsolan-2-yl-7-hydroxy 4,6-Di-1,3,2-dithiarsolan-2-yl-7-hydroxy-3H-phenoxazin-3-one

Description	ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	ReAsH-EDT2 tags with GyrB.FGFR1KD.TC can appear with red fluorescence.
References	[1]. Adams SR, et, al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34. [2]. Perdios L, et, al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv Biol Regul. 2016 Jan;60:6-13.